An-Nas ('Mankind'), 6 Meccan verses, seals the Quran as the second of the two refuge surahs. It seeks protection with the Lord, King and God of mankind from 'the whisperer who withdraws,' the insinuation that comes among jinn and people (114:4-6). With Al-Falaq it is recited for protection and over the sick.
As the Quran's final surah, An-Nas is read by commentators as closing the whole revelation on a note that mirrors its opening: where Al-Fatiha begins the Quran by petitioning for guidance, An-Nas ends it by seeking refuge from the whisper that would lead a person away from that guidance. Ibn Kathir's commentary reads the surah's threefold description of God, as Lord, King and God of mankind, as a deliberate escalation, moving from the intimate relation of sustainer to the sovereign relation of ruler to the ultimate relation of deity, so that the refuge sought is grounded in every register of divine authority at once. The 'whisperer who withdraws' (114:4) is glossed in the classical tradition as Satan, who is described as retreating whenever God is remembered, making the remembrance of God itself, rather than any external act, the surah's implicit remedy. Together with Al-Falaq, An-Nas forms the pair classical scholars call Al-Mu'awwidhatayn, the two seeking-refuge surahs, a name drawn directly from the phrase say, I seek refuge, that opens each of them, and by which the two are still most commonly known in Islamic devotional literature.