The fourth creation succeeded where the others failed because maize, ground into dough by the grandmother goddesses Ixmucane and Ixpiyacoc, gave the first four men Balam Quitze, Balam Aq'ab, Mahucutah and Iqui Balam not just bodies but genuine intelligence, clear sight and proper speech, so capable that the text says the gods grew concerned these first humans could see and understand too much, rivaling their makers, and deliberately clouded their vision to limit it to what was near at hand rather than the whole of creation. In K'iche' cosmology this made maize not merely a staple food but the literal substance of human flesh, a doctrine that reframes agriculture itself as intimately bound up with human origin and ongoing dependence on the gods.
This connection between maize and human life did not begin with the Popol Vuh's colonial-era transcription around 1554 to 1558 CE. Classic period Maya art, produced many centuries earlier, already shows an elaborate Maize God whose cycle of death and rebirth parallels the planting, growth and harvest of the crop itself, evidence that the theological link between maize and human life was deeply established well before the Popol Vuh gave it its fullest surviving narrative form.