Ophiuchus is treated elsewhere on this site chiefly through the recurring, overstated claim of a thirteenth zodiac sign. Set that argument aside, and the constellation holds a genuinely remarkable object with nothing to do with astrology at all: the star with the largest known proper motion of any star in the sky.
Barnard's Star, discovered by the American astronomer E. E. Barnard in 1916, moves across the sky faster, relative to the background stars, than any other star known, a motion large enough to be measured across a human lifetime by careful observation rather than requiring instruments sensitive to changes over centuries. It is also the second-closest stellar system to the Sun after the Alpha Centauri system, close enough and fast-moving enough that its position noticeably shifts against more distant background stars over just a few decades, an effect essentially imperceptible for almost every other star in the sky.
Proper motion of this kind reflects a star's actual velocity through space relative to the Sun combined with its relative closeness, since a star moving at any given real speed appears to shift faster across the sky the nearer it is to an observer, the same reason a passing car appears to move faster than a distant plane travelling at a similar true speed.
The serpent-bearer, invoked every few years in stories about a missing thirteenth sign, quietly holds the fastest-moving star anyone has ever measured.