A Greek papyrus fragment discovered in Egypt and now held in the John Rylands Library in Manchester, generally dated by papyrologists to the third or possibly fourth century, preserves the text of Sub Tuum Praesidium and constitutes, on most scholarly assessments, the earliest surviving prayer addressed directly to Mary rather than simply mentioning her within a narrative or doctrinal text. Its discovery in the twentieth century pushed back by a considerable margin what historians of early Christianity had previously assumed about how quickly direct devotional address to Mary developed, since earlier scholarly consensus had generally dated the emergence of such prayers to the later, post-Nicene fourth and fifth centuries when Marian doctrine was more fully articulated.
The prayer's short text, asking Mary's protection from dangers and deliverance from every peril, uses the Greek term theotokos, God-bearer, a title that would become doctrinally central and fiercely contested at the Council of Ephesus in 431, which has made the papyrus's possible early date a point of real interest and some scholarly caution, since an early witness to that specific title carries theological weight beyond its value as a simple prayer text.