Multiple archaeological finds across the Americas have been proposed as early evidence of tobacco use, but which specific, securely dated find or residue analysis is genuinely the earliest has not been confirmed here.
What would resolve this A residue analysis study identifying nicotine biomarkers from a securely dated, named excavation, compared against other candidate early pipe finds.
OpenArchaeobotany, archaeochemistryMircea Eliade (ed.); Lindsay Jones (ed., 2nd ed.), Encyclopedia of Religion