The Left Angle Cross of Cycles is named for Gate 54 and Gate 53. Human Design reads Gate 54, from Hexagram 54, The Marrying Maiden, sitting in the Root, as ambition, the drive to rise and transform one's material circumstances; and Gate 53, from Hexagram 53, Development, sitting in the Root, as the pressure to begin, an impulse that starts new cycles and often has no interest in seeing them through. It belongs to the Left Angle family, read as transpersonal, a direction practitioners describe as answering less to personal choice than to what circumstance hands the individual.
Its design half is Gate 32 and Gate 42. Gate 32 sits in the Spleen and is read as an instinct for what will last, and caution about change undertaken for its own sake; it pairs with Gate 54 in the channel of Transformation. Gate 42 sits in the Sacral centre and is read as the energy to carry a process through to its natural end; it pairs with Gate 53 in the channel of Maturation.
So a chart carrying this cross rises and begins on a shared Root surface, while beneath it a caution about lasting answers to an energy that finishes what it is given. The same pair also underlies the Cross of Beginnings and the Cross of Ambition, and this cross's own reversal is the Left Angle Cross of Cycles. The hexagrams are ancient; grouping them into one transpersonal cross is the modern system's own construction, dated to 1987.