The Left Angle Cross of Separation is named for Gate 5 and Gate 35. Human Design reads Gate 5, from Hexagram 5, Waiting, sitting in the Sacral centre, as fixed rhythm, an inner timing that keeps eating, sleeping and working patterned; and Gate 35, from Hexagram 35, Progress, sitting in the Throat, as a hunger for progress and for the feeling only a new experience can supply. It sits in the Left Angle family, and Human Design reads that group as outward facing, less a chosen plan than a role other people keep handing back.
Its design half is Gate 47 and Gate 22. Gate 47 sits in the Ajna and is read as a mind working over confusion, sometimes for a long time, until sense finally arrives of itself; it pairs with Gate 64 in the channel of Abstraction. Gate 22 sits in the Solar Plexus and is read as a social grace that flows or withdraws with the emotional wave rather than on demand; it pairs with Gate 12 in the channel of Openness.
So a chart carrying this cross holds a fixed bodily rhythm against a restless hunger for progress on the surface, while beneath it an unresolved mind waits on a mood it cannot command. The same pair of gates, mirrored, also underlies the Cross of Habits, and reversed again the Cross of Experience, with this exact ordering also forming the mirrored Cross of Separation. The numbers are inherited from the I Ching; reading them as one cross belongs to the modern reading, not the classical one.