Vertex is the name the older astrological star lists give to the position of the Great Andromeda Nebula, catalogued as M31, which is not a star at all but the nearest large spiral galaxy to our own, some two and a half million light years away. It was recorded as a nebulous patch by the Persian astronomer al-Sufi in the tenth century and remained a nebula in the catalogues until the 1920s, when Edwin Hubble resolved Cepheid variables within it and established that it lies far outside the Milky Way, a discovery that enlarged the known universe at a stroke. The astrological tradition, working from lists compiled long before that, treats it as a fixed point of the constellation of the chained princess and gives it the general character of a nebulous object, which in that tradition is read cautiously and with reference to the eyes.
Al-Sufi's tenth-century description in his Book of Fixed Stars calls it a "little cloud", and it is very likely the earliest surviving written record of the galaxy, predating the first known telescopic observation by more than six centuries. The Andromeda Galaxy is, at roughly two hundred and twenty thousand light years across, considerably larger than the Milky Way, and the two are approaching each other at around one hundred and ten kilometres per second, on a trajectory current modelling suggests will bring them into a slow, disruptive merger roughly four billion years from now, long after the Sun has left the main sequence.
Sources The Arabs and the StarsPaul Kunitzsch with AstronomyAndrew Fraknoi, David Morrison, and Sidney C. Wolff (OpenStax)