The Gene Keys has a clear and recent lineage, and the system does not conceal it.
It was developed by Richard Rudd, a British author who came to the material through Human Design. Rudd studied and taught with Ra Uru Hu, the originator of Human Design, over roughly the period 1997 to 2004, brought that system to Britain, and ran a school that trained a considerable number of students in it. He began synthesising his own material around 2002 and published The Gene Keys: Unlocking the Higher Purpose Hidden in Your DNA in 2009.
That sequence should be stated in the right order, because the two systems are often encountered as siblings when they are in fact parent and child. Human Design dates from 1987. The Gene Keys is a derivative of it, developed by a senior teacher of that system who then diverged from it. The sixty-four correspondences, the hexagram numbering, the pairing of keys into programming partners, the underlying wheel: all of these Rudd carried over intact from Human Design rather than deriving independently.
What he changed is the use. Human Design is mechanical and prescriptive: it calculates a chart, assigns a type, and issues a strategy and an authority to be experimented with. The Gene Keys is contemplative. It gives no strategy and no rule of conduct. It offers each of the sixty-four as a spectrum to be sat with over a long period, and treats the reading of one's own chart as an occasion for reflection rather than as a set of instructions.
The result is a system that shares an entire skeleton with its predecessor and almost none of its temperament. Neither is ancient. Human Design is roughly forty years old and the Gene Keys is younger still, published in the first decade of this century.