Na is the dental nasal, closing the fourth class, and it is the commonest of the five nasals by a wide margin. It is also the only one that freely begins a Sanskrit word, so it is met as an independent letter constantly rather than only inside clusters, which is unusual among the nasals.
It is the source of most retroflex nasals in the language as well. A rule converts this letter into the retroflex nasal when certain sounds have occurred earlier in the same word, so a reader who sees the retroflex form is usually looking at what began as this one, and a scribe writing either has to know the rule.
In Buddhist vocabulary written in Siddham the letter is everywhere: in the negative prefix in its pre-vocalic form, in the words for name and for man, and in a long list of doctrinal terms. Its frequency puts it in the same class as the voiced dental stop for palaeographic purposes, among the letters whose form varies most between hands and therefore carries the most information about a page.
Its position at the close of the dental class is fixed by the same principle that governs the other four, each of which ends with the nasal made at its own point of articulation.
Its role as the source of the retroflex nasal gives it two written outcomes, and a reader working backwards from a page has to know which rule produced which. That is a small illustration of a general point about the script: what is written is the finished form, and recovering what went into it is grammar rather than recognition.